Contract Manufacturing – Biosafety Level 1.
SEED BANK CREATIONS
- Wild type & Recombinant Seed Bank Creation
- High Cell Density Seed Bank Creation
FERMENTATION AND BIOTRANSFORMATION
- 5L, 40L and 160L Fermentation in batch, fed-batch and continuous modes
- Psychrophilic, mesophilic, thermophilic, aerobic, anaerobic, and microaerophilic submerged fermentations both in constitutive and inducible modes
- Microbial and yeast fermentations for the expression of proteins, peptides and enzymes
- Biotransformation of chemical molecules using microorganisms
- Flow chemistry using microorganisms or immobilized enzymes
PROTEIN PURIFICATION
- Ion Exchange chromatography
- Hydrophobic Interaction chromatography
- Affinity chromatography
- Tangential Flow Filtration (Concentration and UF/DF)
- Dialysis
- Centrifugation
- Depth filtration
PROTEIN FORMULATION
- Stabilizers and excipients selection
- Liquid formulation
- Formulations for freeze drying
- Liquid emulsions
FILLING OF DEVICE COMPONENTS & SMALL CONTAINERS
- Glass vials
- Microtubes
- Polypropylene vials
- Device disposables
LYOPHILIZATION
- Reagents in device components
- Proteins, Enzymes, Peptides
- Bulk lyophilization
- IBEX has over 30 years of experience in microbial fermentation and purification.
- IBEX produces proteins in a variety of hosts.
- IBEX produces multiple enzymes which are used in medical devices worldwide.